What is trimethobenzamide used for?
Trimethobenzamide is used to treat nausea and vomiting after surgery. It is also used to treat nausea caused by gastroenteritis.
What is Tigan injection used for?
Tigan® is indicated for the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Can trimethobenzamide be given IV?
Trimethobenzamide injection is for intramuscular administration only; do not give via intravenous administration. Trimethobenzamide injection is contraindicated for use in children or infants. Trimethobenzamide suppositories are contraindicated for use in neonates and premature neonates.
How long does it take for trimethobenzamide to work?
Trimethobenzamide (Tigan) takes about 10 to 40 minutes to kick in. Its effects can last up to 4 hours.
What is trimethobenzamide 300 mg used for?
Trimethobenzamide is used to treat nausea and vomiting that may occur after surgery. It is also used to control nausea caused by gastroenteritis (‘stomach flu’; a virus that may cause nausea, vomiting, and diarrhea). Trimethobenzamide is in a class of medications called antihistamines.
What is the action of Tigan?
Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting.
Which injection can stop vomiting?
Metoclopramide Injection belongs to a group of medicines known as antiemetics. Antiemetics stop or prevent nausea and vomiting. Metoclopramide Injection may be used for the management of other conditions that are not mentioned above.
What class of drug is Tigan?
Tigan belongs to a class of drugs called Antiemetic Agents.
Can Tigan be given intravenously?
Trimethobenzamide injection is for intramuscular administration only; do not give via intravenous administration. Trimethobenzamide injection is contraindicated for use in children or infants.
Why is Trimethobenzamide being discontinued?
Trimethobenzamide used to be available also as suppositories, but this formulation was discontinued due to lack of efficacy.
Has trimethobenzamide been discontinued?
All generic trimethobenzamide oral capsules have been discontinued. Pfizer discontinued oral Tigan. They expect supplies to be depleted by May 2021.
Does Tigan make you sleepy?
Diarrhea, headache, dizziness, drowsiness, or blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Does trimethobenzamide prolong QTc?
Based on the results of this retrospective analysis, trimethobenzamide was shown to be effective in reducing N/V symptoms while not prolonging the QTc interval further.
Is trimethobenzamide an antiemetic?
Trimethobenzamide is an orally available, antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses.
Can trimethobenzamide make you sleepy?
Diarrhea, headache, dizziness, drowsiness, or blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
Can you give Tigan IV?
How long does a Tigan injection last?
The mean elimination half-life of trimethobenzamide is 7 to 9 hours. Between 30 – 50% of a single dose in humans is excreted unchanged in the urine within 48 – 72 hours.
What happens if you give Phenergan IV?
Phenergan Injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration.