Can linoleic acid contribute to coronary artery disease?
The adipose tissue concentration of linoleic acid was positively associated with the degree of coronary artery disease (CAD) in a cross-sectional study of 226 patients undergoing coronary angiography. Linoleic acid concentration in adipose tissue is known to reflect the intake of this fatty acid.
Does alpha linolenic acid prevent heart disease?
Data synthesis: Alpha-linolenic acid (ALA) is one of the two essential fatty acids in humans. Epidemiological studies and dietary trials strongly suggest that this fatty acid is important in relation with the pathogenesis (and prevention) of coronary heart disease.
Which fatty acids are correlated with coronary heart disease?
In all multivariate models, levels of the cholesterol ester saturated fatty acid palmitic acid (16:0) were directly associated with CHD risk (standardized odds ratio = 1.68; 95% confidence interval 1.10-2.55 in the model that adjusted for total plasma cholesterol level).
What fatty acids reduce the risk of coronary heart disease?
Our findings that fish and omega-3 fatty acid consumption was associated with a lower risk of overall mortality were consistent with those in other trials. In our cohort, omega-3 fatty acid intake and fish consumption were associated with a significantly lower risk of CHD.
Is linoleic acid the same as omega-6?
There are several different types of omega-6 fatty acids, and not all promote inflammation. Most omega-6 fatty acids in the diet come from vegetable oils, such as linoleic acid (LA), not to be confused with alpha-linolenic acid (ALA), which is an omega-3 fatty acid.
Is linoleic acid unhealthy?
Concerns have been raised about higher linoleic acid consumption being harmful for heart health because of potential pro-inflammatory and thrombogenic properties. Linoleic acid can be elongated to arachidonic acid and subsequently synthesized to a variety of pro-inflammatory eicosanoids, which may increase CHD risk.
What is the function of linoleic acid?
As part of membrane phospholipids, linoleic acid functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis.
What is another name for linoleic acid?
The two main fatty acids that are essential in the diet are linoleic acid, which is otherwise referred to as omega-6, and alpha-linolenic acid, or omega-3.
How can a high fat diet lead to coronary heart disease?
The classic diet-heart hypothesis posits that diets high in saturated fatty acids (SFAs) and cholesterol and low in polyunsaturated fatty acids (PUFAs) raise serum total and LDL cholesterol, which in turn increase the risk of coronary heart disease (CHD) (1).
Why is linoleic acid bad?
Why is linoleic acid bad for you?
Does a high fat diet cause clogged arteries?
It is common knowledge supported by health experts, the American Heart Association and the World Heart Federation: Eating saturated fats will cause plaque to build up in the arteries, which then harden, and ultimately leads to coronary heart disease.
Is linoleic acid proinflammatory?
In conclusion, evidence generated over the past decade shows linoleic acid intake is associated with lower risk of chronic disease and is not pro-inflammatory.
Is high linoleic acid good?
Linoleic acid is found in plant-based oils, nuts and seeds, and it is the most common polyunsaturated omega 6 fatty acid. A high intake and high levels of linoleic acid in the blood have been associated with a reduced risk of type 2 diabetes and cardiovascular disease.