How effective is cisplatin and gemcitabine?

How effective is cisplatin and gemcitabine?

Cisplatin plus gemcitabine significantly improved progression-free survival, with a median of 8.0 months (95% CI, 6.6 to 8.6) in the cisplatin–gemcitabine group as compared with 5.0 months (95% CI, 4.0 to 5.9) in the gemcitabine-only group (P<0.001).

Can gemcitabine and cisplatin cure cancer?

We conclude that gemcitabine in combination with cisplatin may be one of the most effective therapies for patients with advanced gallbladder cancer. If confirmed by others, it may provide an important therapeutic option in managing these patients who otherwise have a dismal prognosis.

Do you lose your hair with gemcitabine?

v Hair loss is typically minimal with gemcitabine, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment. v Nausea and vomiting are not unusual but are less common today than in the past because of much improved anti-nausea medications.

Does Gemzar go before cisplatin?

The recommendation to administer gemcitabine prior to cisplatin is based on results of phase 1 studies in adults with solid tumors, which indicated that this administration schedule may increase the generation of platinum-DNA adducts (potentially increasing efficacy) and reduce neutropenia.

How dangerous is the chemo drug cisplatin?

Warnings. Cisplatin can affect your nervous system, increase your risk of bleeding or infection, or harm your kidneys. Call your doctor if you have a fever, mouth sores, cough, sore throat, unusual bleeding or bruising, hearing problems, numbness or tingling in your hands or feet, little or no urinating, swelling or rapid weight gain, or shortness of breath.

What are the uses of gemcitabine and docetaxel?

Study objectives. The primary aim of this study is to analyse the GD therapy effect on progression-free survival (PFS).

  • Design.
  • Patient cohort.
  • Target sample size and rationale.
  • Study treatment.
  • Outcomes.
  • Statistical analysis.
  • How effective is gemcitabine for pancreatic cancer?

    3.1. Characterization of gemcitabine-loaded PEGcPAMAM-PEG dendrimers.

  • 3.2. Gemcitabine was successfully released from the dendrimers.
  • 3.3. Effect of gemcitabine-loaded PEGcPAMAM-PEG dendrimers on CFPAC-1 pancreatic cancer cells’ viability.
  • 3.4.
  • 3.5.
  • 3.6.
  • Can gemcitabine plus cisplatin be used in metastatic cancer?

    These data provide evidence that cisplatin plus gemcitabine is an effective treatment option for locally advanced or metastatic biliary tract cancer. Patients treated with cisplatin plus gemcitabine lived an average of 3.6 months longer than those treated with gemcitabine alone.