What is extramedullary plasmacytoma?

What is extramedullary plasmacytoma?

Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma.

How do you diagnose plasmacytoma?

Diagnosis and Tests Computed tomography (CT) scan: This test uses a series of X-rays and a computer to produce a 3D image of soft tissues and bones. Providers use CT scans to look for possible bone damage caused by plasmacytoma.

What is extramedullary?

Extramedullary disease (EMD) occurs when myeloma cells form tumors outside the bone marrow in the soft tissues or organs of the body. While myeloma resides mainly within the bone marrow, EMD can be present at the time of initial diagnosis or at the time of disease relapse following treatment-induced remission.

What is an extramedullary tumor?

An intradural extramedullary tumor is a spinal cord tumor that causes spinal cord compression — nerves in and around the spinal cord are compressed as the tumor grows in size. The vast majority of these tumors are benign and treated with surgery.

What is extramedullary tumor?

Extramedullary plasmacytoma, also known as extraosseous plasmacytoma , are the less common form of solitary plasmacytoma, manifesting as isolated plasma cell tumors located at a non-osseous site. In contrast to multiple myeloma, solitary plasmacytomas have little or no systemic bone marrow involvement.

Does solitary extramedullary plasmacytoma appear on CT and MR imaging?

BACKGROUND AND PURPOSE: Solitary extramedullary plasmacytoma (SEP) is rare. The purpose of this study was to determine the CT and MR imaging features of SEP of the nasal tract. METHODS: We retrospectively reviewed three CT and two MR images of three histologically proved cases in two men and one woman aged 43–66 years.

How is extramedullary plasmacytoma diagnosed?

The diagnosis of extramedullary plasmacytoma was established on the basis of the presence of large aggregates of atypical plasma cells that often infiltrated adjacent structures. The monoclonal nature of the plasma cells was confirmed by means of immunoperoxidase staining for kappa and lambda immunoglobulin light chains.

What are the treatment options for extramedullary plasmacytoma of the head and neck?

Immunoperoxidase characterization of extramedullary plasmacytoma of the head and neck. Head Neck Surg 1987;9:356–361 Ikeda K, Takasaka T. Endoscopic laser sinus surgery using KTP/532 laser. Lasers Med Sci 1996;11:133–138