What is hyperplasia of the uterus?
When the endometrium, the lining of the uterus, becomes too thick, it is called endometrial hyperplasia. This condition is not cancer, but in some cases, it can lead to cancer of the uterus.
What causes hyperplasia of the uterus?
Endometrial hyperplasia is caused by too much estrogen and not enough progesterone. If there’s too little progesterone, your uterus isn’t triggered to shed its lining (menstruation). The lining continues to thicken due to estrogen. The cells in the lining may crowd together and become irregular.
How long does it take for endometrial hyperplasia to turn into cancer?
In one study, hyperplasia without atypia progressed to endometrial carcinoma in fewer than 5% of women; in comparison, atypical hyperplasia progressed to endometrial carcinoma in one in eight women within 10 years, and in one in three women within 20 years.
What is the treatment for endometrial hyperplasia?
Endometrial hyperplasia treatment The most common treatment is progestin. This can be taken in several forms, including pill, shot, vaginal cream, or intrauterine device. Atypical types of endometrial hyperplasia, especially complex, increase your risk of getting cancer.
Should you have a hysterectomy if you have endometrial hyperplasia?
If you’re at increased risk of cancer due to atypical endometrial hyperplasia, your healthcare provider may recommend a hysterectomy to remove the uterus. After a hysterectomy, you won’t be able to get pregnant. Many people see symptoms improve with less invasive progestin treatments.
Is hysterectomy necessary for endometrial hyperplasia?
Is endometrial hyperplasia curable?
This condition may improve without treatment. Hormone therapy helps in some cases. Simple or complex atypical endometrial hyperplasia: An overgrowth of abnormal cells causes this precancerous condition. Without treatment, your risk of endometrial or uterine cancer increases.
Is endometrial hyperplasia precancerous?
Simple or complex atypical endometrial hyperplasia: An overgrowth of abnormal cells causes this precancerous condition. Without treatment, your risk of endometrial or uterine cancer increases.
Does endometrial hyperplasia cause weight gain?
Endometriosis is an estrogen-dependent disease, which means that its symptoms may worsen when estrogen levels are higher. However, there is no evidence that this can cause weight gain.
What are the signs and symptoms of endometrial hyperplasia?
What are the symptoms of endometrial hyperplasia?
- Abnormal menstruation, such as short menstrual cycles, unusually long periods or missed periods.
- Heavy menstrual bleeding).
- Bleeding after menopause (when periods stop).
Is endometrial hyperplasia life threatening?
Some endometrial hyperplasias are more serious than others. For example, there is a less than 5% chance that endometrial hyperplasia without atypia will progress to cancer over the course of 20 years. In contrast, around 8–30% of atypical endometrial hyperplasia cases will develop into cancer.
How does endometrial hyperplasia affect the uterus?
The progesterone drop triggers the uterus to shed its lining as a menstrual period. Women who have endometrial hyperplasia make little, if any, progesterone. As a result, the uterus doesn’t shed the endometrial lining. Instead, the lining continues to grow and thicken.
What is the difference between hyperplasia and uterine cancer?
Uterine Hyperplasia and Cancer. Hyperplasia is an overgrowth of the uterine lining that in some cases can develop into uterine cancer. Types of endometrial hyperplasia differ based on the characteristics of the cells found in the biopsy sample.
What are the treatment options for hyperplasia of the uterus?
Oral progesterone, Depo-Provera (injection), or an Intrauterine Device (IUD) are all possible treatment options. Progesterone counteracts the effects of estrogen and thins the uterine lining. Endometrial sampling after the progesterone treatment should be used to assess resolution. Resolution of hyperplasia occurs in almost 80 percent of cases.
What does precancerous endometrial hyperplasia mean?
This type is marked by an overgrowth of unusual cells and is considered precancerous. Precancerous means that there’s a chance it could turn into uterine cancer without treatment. Knowing the type of endometrial hyperplasia you have can help you better understand your cancer risk and choose the most effective treatment.