What is Rubidium 82 chloride used for?
Rubidium chloride Rb-82 is a radiopharmaceutical diagnostic agent used for Positron Emission Tomography (PET) imaging of the myocardium to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
What does Rb-82 decay to?
Rubidium Rb 82 decays by positron emission and associat- ed gamma emission with a physical half-life of 75 seconds.
What is Rb-82 clinically used for what are the clinical indications for a physician to request for this type of scan?
Rubidium Rb 82 chloride injection is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
How does a rubidium 82 generator work?
Rubidium-82 is produced through beta plus decay from its parent nucleus, strontium-82. The generator contains accelerator produced 82Sr adsorbed on stannic oxide in a lead-shielded column and provides a means for obtaining sterile nonpyrogenic solutions of RbCl(Halide salt form capable of injection).
What do PET scans show?
The PET scan uses a radioactive drug (tracer) to show both normal and abnormal metabolic activity. A PET scan can often detect the abnormal metabolism of the tracer in diseases before the disease shows up on other imaging tests, such as computerized tomography (CT) and magnetic resonance imaging (MRI).
What is nuclear medicine myocardial perfusion stress test?
Myocardial perfusion is an imaging test. It’s also called a nuclear stress test. It is done to show how well blood flows through the heart muscle. It also shows how well the heart muscle is pumping.
What is Ruby fill?
RUBY-FILL is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use.
How much does a rubidium generator cost?
Providers need to know they have enough patients to afford the rubidium generator, which can cost as much as $450,000 per year when including shipping and all equipment.
Why would a doctor recommend a PET scan?
Your doctor may order a PET scan to inspect your blood flow, your oxygen intake, or the metabolism of your organs and tissues. PET scans show problems at the cellular level, giving your doctor the best view of complex systemic diseases. PET scans are most commonly used to detect: cancer.
What is a rubidium heart scan?
Rubidium Rb 82 injection is used in adults to help diagnose heart disease. It is used in a procedure called a positron emission tomography (PET) scan to help your doctor see an image of your heart. This medicine shows how much blood is getting to your heart muscle when you are resting or exercising (stressed).
How much is a cardiac pet?
Specific PET Scan Procedures and National Cost Averages
| Procedure | Price Range |
|---|---|
| Whole Body PET Scan Cost Average | $3,300 – $12,000 |
| PET Scan (Chest to Head Neck) Cost Average | $3,000 – $10,700 |
| PET Scan Heart Cost Average | $2,850 – $24,200 |
| PET Scan Brain Cost Average | $2,250 – $10,700 |
What medications should not be taken before a nuclear stress test?
Medications with caffeine: Do not take any over-the-counter medication that contains caffeine (such as Excedrin®, Anacin®, diet pills and NoDoz®) for 24 hours before the test.
How do you feel after a nuclear stress test?
Dizziness or chest pain. These symptoms can occur during a nuclear stress test. Some people also have nausea, shakiness, headache, flushing, shortness of breath and anxiety during the stress test.
What is the standard state of Rubidium-82 chloride?
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Rubidium-82 chloride is a form of rubidium chloride containing a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging.
How much rubidium Rb 82 chloride should be injected?
The recommended adult (70 kg) single dose of rubidium Rb 82 chloride injection is 1,480 MBq (40 mCi), with a range of 1,110 MBq to 2,220 MBq (30 mCi to 60 mCi). Do not exceed a single dose of 2,220 MBq (60 mCi) per rest or stress component of a procedure. (2.2) Use the lowest dose necessary to obtain adequate cardiac visualization.
What is the half life of rubidium 82?
Rubidium-82 is a potassium analog and behaves in vivo much as thallium-201 does. Its extraction fraction is about 50% to 60% at rest. It has a half-life of 76 seconds and more energetic positron emissions than F-18, rendering a less favorable image resolution.
How do you make rubidium 82 SR?
Rubidium-82 is produced through beta plus decay from its parent nucleus, strontium-82. The generator contains accelerator produced 82 Sr adsorbed on stannic oxide in a lead-shielded column and provides a means for obtaining sterile nonpyrogenic solutions of RbCl (Halide salt form capable of injection).