What is Semglee insulin?

What is Semglee insulin?

Semglee (insulin glargine-yfgn) is the first interchangeable biosimilar product approved in the U.S. for the treatment of diabetes. Approval of these insulin products can provide patients with additional safe, high-quality and potentially cost-effective options for treating diabetes.

What is the difference between Semglee and Semglee YFGN?

Semglee contains a slightly different form of insulin glargine called insulin glargine-yfgn. But since it’s a biosimilar to Lantus, there are no clinically meaningful differences between the two products. This means that Semglee is just as effective as Lantus in helping you manage your blood sugar.

What is one unit of insulin?

Officially, one unit is defined at the biological equivalent of 34.7 micrograms of pure crystalline insulin, a measure that comes from the dawn of insulin, and just happens to be the amount required to induce hypoglycemia in a rabbit (don’t ask).

Is Basaglar the same as Semglee?

Semglee is a biosimilar insulin glargine, meaning it’s interchangeable with other insulin glargine products such as Lantus, Toujeo, and Basaglar. “Biosimilars are like generics for biologics,” Joanna Lewis, PharmD, MBA, a pharmacist in Florida, told Healthline.

Does Semglee insulin make you gain weight?

Adverse reactions associated with insulin glargine (the active ingredient contained in Semglee) include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus, rash, edema, and weight gain.

When should I take Semglee insulin?

Semglee is injected under the skin, usually once per day at the same time of day. When treating type 1 diabetes, use your short-acting insulin before meals as directed by your doctor. Semglee must not be given with an insulin pump, or mixed with other insulins.

Are Semglee and Lantus the same?

Semglee carries the same scientific indications and amino acid sequence as Lantus, so for all practical purposes, it is a lower-cost version of the same drug. Technically, Semglee is not a “generic,” but is officially considered a “follow-on” insulin, which basically means it’s a copy of an already-approved product.

Are Lantus and Semglee interchangeable?

Semglee (insulin glargine-yfgn) is both biosimilar to, and interchangeable with, its reference product, Sanofi’s Lantus (insulin glargine). Being interchangeable means that Semglee doesn’t need to be explicitly prescribed and can be substituted for Lantus by a pharmacist who is filling the prescription.

How do you read a 40 unit insulin syringe?

Understanding Insulin Strengths The numbers 40 or 100 refer to how much insulin (the number of units) is in a set volume of fluid – which, in this case, is one milliliter (1 ml) [referred to as units per ml]. For example, U-100 insulin has 100 units per milliliter and U-40 has 40 units per milliliter.

Can Semglee be interchanged with Basaglar?

“Pharmacists should understand that Semglee can be substituted for Lantus without intervention of the prescriber, but currently cannot be interchanged with Basaglar–Lilly, another insulin glargine product on the market,” she said.

Has Semglee insulin been discontinued?

SEMGLEE (insulin glargine-yfgn) and Insulin Glargine (insulin glargine-yfgn), co-developed by Viatris and Biocon Biologics, are now available in the U.S. market. The currently marketed non-interchangeable SEMGLEE (insulin glargine) is anticipated to be phased out by the end of the 2021 calendar year.

How long does it take Semglee to work?

Semglee (Subcutaneous) Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Insulin glargine is used to improve blood sugar control in people with diabetes mellitus.

What are the side effects of Semglee insulin?

Side effects of Semglee include:

  • low blood sugar (hypoglycemia),
  • allergic reactions,
  • injection site reactions,
  • changes in body fat distribution (lipodystrophy),
  • itching,
  • rash,
  • fluid retention (edema),
  • and weight gain.

Does Semglee insulin cause weight gain?

Does Semglee make you gain weight?

Common side effects may include: low blood sugar; swelling, weight gain; allergic reaction, itching, rash; or.

Is Semglee being discontinued?

The currently marketed non-interchangeable SEMGLEE (insulin glargine) is anticipated to be phased out by the end of the 2021 calendar year.

How much cheaper is Semglee than Lantus?

Semglee is available by prescription in either a pen or a vial – it costs $147.98 for five 3 mL pre-filled pens or $98.65 for one 10 mL vial, which is a 65% discount from the list price of Lantus.

How many mL is 40 units?

0.40 mls
How to Convert Insulin Units to Milliliters (ml) Using U-100 Insulin

To administer this amount of U-100 insulin Draw to this level in a 1 ml syringe
37 units 0.37 mls
38 units 0.38 mls
39 units 0.39 mls
40 units 0.40 mls