What is the difference between epoetin alfa and epoetin beta?
Epoetin beta was found to differ from epoetin alfa in containing: (a) a greater proportion of more basic isoforms, (b) a greater proportion of EPO binding to Erythrina cristagalli agglutinin (which binds N-glycans with nonsialylated outer Gal beta1-4GlcNAc moieties), and (c) isoforms with higher in-vivo:in-vitro …
Is epoetin and Procrit the same?
PROCRIT® (epoetin alfa) is used to treat a lower than normal number of red blood cells (anemia) caused by: Chronic kidney disease in patients on dialysis and not on dialysis.
Is Epogen and Procrit the same?
Epogen and Procrit are both epoetin alfa, but they are marketed by two different pharmaceutical companies. The FDA approved epoetin alfa in June 1989.
Is epoetin alfa the same as Epogen?
Epogen (epoetin alfa) is an injectable medication used to treat low red blood cell count. It can have serious side effects, so it should only be used in certain types of people with anemia.
Is epoetin and erythropoietin the same?
Descriptions. Epoetin injection is a man-made version of human erythropoietin (EPO). EPO is produced naturally in the body, mostly by the kidneys. It stimulates the bone marrow to produce red blood cells.
What is epoetin beta used for?
Methoxy polyethylene glycol-epoetin beta injection is used to treat anemia in adults with chronic kidney disease (CKD) who may or may not be on dialysis or in children with CKD who are on dialysis.
What is a substitute for PROCRIT?
On May 15, 2018, the Food and Drug Administration approved Retacrit (epoetin alfa-epbx, Hospira Inc., a subsidiary of Pfizer Inc.)
Is erythropoietin the same as epoetin?
Is Epogen cheaper than Procrit?
Epogen and Procrit are specialty medications used to treat anemia caused by chronic kidney disease (CKD) or chemotherapy, but they don’t come cheap. A 30-day supply of Procrit costs well over $2,000 and prices for Epogen average around $600 per month.
What is another name for PROCRIT?
Procrit and Epogen are the trade names for epoetin alfa. In some cases, health care professionals may use the trade names Procrit or Epogen when referring to the generic drug name epoetin alfa. Drug Type: Epoetin alfa is a colony stimulating factor.
Is Epogen cheaper than PROCRIT?
Is erythropoietin the same as EPOGEN?
EPOGEN® is a prescription medicine for people on dialysis with anemia due to CKD that acts like a hormone called erythropoietin (ee-rith-row-PO-eh-tin). This hormone plays an important role in making red blood cells. EPOGEN® is used to treat anemia by helping the body create more red blood cells.
How do you inject epoetin with Alfa?
Adults—Dose is based on body weight and must be determined by your doctor. The starting dose is 100 units per kilogram (kg) injected into a vein or under the skin three times a week for 8 weeks. Your doctor may adjust the dose as needed. Children—Use and dose must be determined by your doctor.
What is the brand name for epoetin?
Procrit and Epogen are the trade names for epoetin alfa.
What is the generic for epoetin?
How long does a PROCRIT shot last?
Throw it away after one use, even if there is still medicine left inside. Throw away any leftover medicine in a multi-dose vial 21 days after the first use.
What is the difference between erythropoietin and epoetin?
Epoetin injection is a man-made version of human erythropoietin (EPO). EPO is produced naturally in the body, mostly by the kidneys. It stimulates the bone marrow to produce red blood cells. If the body does not produce enough EPO, severe anemia can occur.
When do you use epoetin alfa?
Epoetin alfa injection products are used to treat anemia (a lower than normal number of red blood cells) in people with chronic kidney failure (condition in which the kidneys slowly and permanently stop working over a period of time).
Is there a substitute for PROCRIT?
When should PROCRIT not be given?
It is not known if PROCRIT® is safe and effective in treating anemia in children less than 1 month old who have chronic kidney disease and in children less than 5 years old who have anemia caused by chemotherapy. Who should not take PROCRIT®?
What is the difference between epoetin alfa and beta?
Epoetin alfa and beta are the two forms of recombinant DNA-derived erythropoietin (rEPO), both synthesized in Chinese hamster ovary cells, which are used for the treatment of erythropoietin (EPO)-responsive anaemias. Several batches of each of these rEPOs were compared for differences in their EPO i …
What is the difference between retacrit (epoetin alfa) and Epogen?
Retacrit (epoetin alfa-epbx), from Hospira, and Epogen, (epoetin alfa), from Amgen, are both erythropoiesis-stimulating agents (ESA) used to help improve red blood cell production.
What are the side effects of epoetin alfa?
See the full epoetin alfa side effects document. Common side effects include: upper respiratory tract infection, arthralgia, decreased serum iron, diarrhea, edema, fever, low serum ferritin, paresthesia, respiratory congestion, skin rash, tachycardia, cough, dyspnea, headache, nausea, signs and symptoms of injection site, and vomiting.
Does epoetin improve solid tumor response to chemotherapy and radiation?
•The data available suggest that neither epoetin nor darbepoetin improves solid tumor response to chemotherapy or radiation therapy. One study found erythropoietic stimulants might decrease survival while another suggested the two drugs might accelerate progression of some tumors. “However, both of these findings remain uncertain,” the report said.