What is the treatment for seminoma?
Stage IIC seminomas Treatment is typically chemotherapy with 4 cycles of EP (etoposide and cisplatin) or 3 or 4 cycles of BEP (bleomycin, etoposide, and cisplatin). Another option might be VIP (etoposide, ifosfamide, and cisplatin) for 4 cycles. Radiation therapy is generally not used for stage IIC seminoma.
Is seminoma cancer curable?
Overview. Patients with Stage II testicular seminoma have a curable cancer that involves the testis and the retroperitoneal lymph nodes.
What happens if you remove 1 testicle?
Losing one testicle usually has no effect on a man’s ability to get an erection and have sex. But if both testicles are removed, sperm cannot be made and a man becomes infertile. Also, without testicles, a man cannot make enough testosterone, which can decrease sex drive and affect his ability to have erections.
What is the prognosis for seminoma?
The 3-year survival rate for patients diagnosed with typical testicular seminoma was 100%, 93.8% for cases with testicular seminoma combined with embryonal carcinoma, and 84.6% for those with testicular seminoma combined with embryonal carcinoma and teratoma.
What causes seminoma cancer?
Later in development, germ cells in males are supposed to mature into sperm-producing cells within the testicles. If the germ cells don’t mature as they are supposed to, they can sometimes change and multiply uncontrollably to form a seminoma or non-seminoma.
Can a person live with one testicle?
Usually, people can live with just one of these organs while maintaining a healthy, normal life. Testicles are no different. But it’s still important to regularly follow up with a doctor, especially if you have an undescended testicle.
How painful is testicle removal?
Most men will have discomfort requiring pain medicine for 1-2 weeks. After this time, the pain usually diminishes considerably, although there may be certain times of day when discomfort is worse. Many men experience the greatest discomfort when sitting or at night. A dull ache or soreness is common for 6-8 weeks.
Does seminoma spread to bone?
Abstract. Isolated muscle and bone metastases are rarely encountered in patients with testicular seminomas. In the present study, a patient who was admitted with pain, loss of motion, and swelling in the right leg 20 months following surgery for stage I seminoma was presented.
What are the treatment options for seminoma?
Radiation therapy: Radiation aimed at para-aortic lymph nodes is another option. These nodes are in the back of the abdomen (belly), around the large blood vessel called the aorta. Because seminoma cells are very sensitive to radiation, low doses can be used. About 10 to 15 treatments are given over 2 to 3 weeks.
What is the difference between intratubular seminoma and IGCNU?
Intratubular seminoma fills and distends the tubules, whereas IGCNU is restricted to the basilar area, although the cells are histologically identical. Atypical germ cells that do not resemble IGCNU cells may also occur in seminiferous tubules. These cells may have large nuclei or be multinucleated.
What is the definitive treatment for intratubular germ cell neoplasia of testis?
Surgical removal of testis, known as orchidectomy, is a definitive treatment for Intratubular Germ Cell Neoplasia of Testis. But since all the lesions do not progress to germ cell tumors, sometimes it can be an ‘over-treatment’ and not recommended as a first choice,…
What are the less frequent growth patterns of seminoma?
Less frequent growth patterns include intertubular pattern (may not form a mass), corded growth, microcystic, tubular, signet ring appearance Comment: Immunohistochemistry was performed and the tumor expresses OCT 3/4 and CD117. The cells are negative with CD30 and AFP. The immunoprofile supports the morphologic interpretation of seminoma.
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