How are nanoparticles used in drug delivery?
Through the manipulation of size, surface characteristics and material used, the nanoparticles can be developed into smart systems, encasing therapeutic and imaging agents as well as bearing stealth property. Further, these systems can deliver drug to specific tissues and provide controlled release therapy.
Which nanoparticle is best for drug delivery?
Polymeric nanoparticles can be categorized into nanospheres and nanocapsules both of which are excellent drug delivery systems. Likewise, compact lipid nanostructures and phospholipids including liposomes and micelles are very useful in targeted drug delivery.
What is a nanoparticle system?
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency.
What drugs use nanoparticles?
Several anti-cancer drugs including paclitaxel, doxorubicin, 5-fluorouracil and dexamethasone have been successfully formulated using nanomaterials. Quantom dots, chitosan, Polylactic/glycolic acid (PLGA) and PLGA-based nanoparticles have also been used for in vitro RNAi delivery.
What are the characteristics of drug delivery system?
Ideal characteristics of drug delivery systems It should increase the bioavailability of the drug. It should transport the drug intact to the site of action while avoiding the non-diseased host tissue. The product should be stable and delivery should be maintained under various physiological variables.
What is the importance of drug delivery system?
A drug delivery system is a formulation or a device that enables the introduction of a therapeutic substance in the body and improves its efficacy and safety by controlling the rate, time and place of release of drugs in the body.