What is the composition of vitamin D3?
Types
| Name | Chemical composition |
|---|---|
| Vitamin D1 | Mixture of molecular compounds of ergocalciferol with lumisterol, 1:1 |
| Vitamin D2 | ergocalciferol (made from ergosterol) |
| Vitamin D3 | cholecalciferol (made from 7-dehydrocholesterol in the skin). |
| Vitamin D4 | 22-dihydroergocalciferol |
What are the properties of vitamin D3?
Vitamin D is the only vitamin that also has hormonal properties. After vitamin D (D3) is made by the skin or acquired through food or supplements, the kidney and liver change it into a hormone. As a hormone, it controls calcium absorption to help the body build strong bones and teeth and maintain muscle strength.
What is calcitriol molecule?
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light.
How is vitamin D3 different from vitamin D?
There are two possible forms of vitamin D in the human body: vitamin D2 and vitamin D3. Both D2 and D3 are simply called “vitamin D,” so there’s no meaningful difference between vitamin D3 and just vitamin D.
What is the best form of vitamin D3?
Healthline’s picks of the best vitamin D supplements
- Pure Encapsulations D3 10,000 IU.
- NOW Foods D3 10,000 IU.
- Pure Encapsulations Vitamin D3 (Vegan) Liquid.
- HUM Nutrition Here Comes the Sun.
- Nordic Naturals Zero Sugar Vitamin D3 Gummies 1,000 IU.
- Thorne Vitamin D/K2.
- Designs for Health Liposomal D Supreme.
Why is vitamin D3 called D3?
Most vitamin D supplements are labeled as D3 because this is the most active form of vitamin D. This form of vitamin D is also more easily absorbed by the body, which means that it can provide more health benefits.
What is the structure of cholecalciferol?
C27H44OCholecalciferol / Formula
What is the mechanism of action of vitamin D3?
The Vitamin D Receptor and Mechanism of Action The active form of vitamin D binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains.
What is the difference between calcitriol and vitamin D3?
Calcitriol, which is actually the most active form of vitamin D [100-times higher than 25(OH)D3] has a very short half-life, of about a few hours. While calcitriol was first thought to be generated solely in the kidney, it is now recognized in many extrarenal tissues (10–12).
How is D3 best absorbed?
Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstream when paired with high-fat foods. For this reason, it’s recommended to take vitamin D supplements with a meal to enhance absorption.
Why is vitamin D3 physiologically important?
The general physiological function of vitamin D is to keep us healthy by promoting strong bones, properly functioning muscles and a potent immune system.
Is vitamin D3 a steroid hormone?
The endogenous serum metabolite of vitamin D (calcitriol, 1,25(OH)2 D3 ) is considered a true steroid hormone (D hormone), and like glucocorticoids (GCs) and gonadal hormones, may exert several immunomodulatory activities.
What is difference between calcitriol and vitamin D3?
What is the difference between Calciferol and calcitriol?
Calcidol is the major circulating metabolite of cholecalciferol, while calcitriol is the hormone that upregulates the active transport of calcium from the gut, and which suppresses parathyroid hormone secretion.
Is 10000 IU of d3 too much?
The Endocrine Society Practice Guidelines recommend that up to 10,000 IUs daily was safe for adults. This is in contrast to the recommended UL at 4,000 IU/d from the IOM.
What is the chemical formula for vitamin D3?
d3-vicotrat; d3-vigantol; 7-dehydrocholesterol; delsterol; deparal; duphafral d3 1000; ebivit; granuvit d3; neo dohyfral d3; oleovitamin d3; provitina; quintox; ricketon; 9,10-secocholesta-5,7,10(19)-trien-3beta-ol; trivitan; vi-de-3-hydrosol; vi-de3; videkhol; vigantol; vigorsan; vitamin d3; vitinc dan-dee-3
What is the structural formula for vitamin D?
Vitamin D without a subscript refers to either D 2 or D 3, or both, and is known collectively as calciferol. Vitamin D 2 was chemically characterized in 1931. In 1935, the chemical structure of vitamin D 3 was defined and shown to result from the ultraviolet irradiation of 7-dehydrocholesterol.
What is the chemical name for vitamin D3?
– high levels of vitamin D in your body (hypervitaminosis D); – high levels of calcium in your blood ( hypercalcemia ); or – any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
What are the types of vitamin D?
D3 version (as Cholecalciferol)